Is the accumulation of fluid in the abdomen. Ascites can occur with both cancer and non-cancerous conditions. When it occurs with ovarian cancer it is usually associated with spread of cancer cells to the lining of the abdomen, or blockage of the lymphatics that would normally drain fluid out of the abdomen.The presence of ascites with ovarian cancerĀ is associated with symptoms of abdominal swelling, bloating indigestion, pain or GI symptoms (nausea, vomiting, constipation).