Also referred to as endometrial cancer, this cancer affects women most often in post-menopause, but can also affect younger women. The cancer originates in the lining of the uterus (womb) and abnormal bleeding is usually an early warning sign. There are several risk factors for this cancer among them obesity, and the use of estrogen only supplements. Abnormal vaginal bleeding including post- menopausal bleeding, inter-menstrual bleeding, or a change in periods to a heavy flow should prompt a visit to your gynecologist.